The serum on the shelf and the injectable in the clinic share the name salmon DNA, and almost nothing else.
PDRN's real evidence, a doubled wound-closure rate in a trial of 216 patients, all came through a needle. The molecule runs 50,000 to 1,500,000 daltons, a hundred to three thousand times past the 500-dalton ceiling for crossing intact skin, so a serum you smooth on cannot carry it to the fibroblasts where it works. The odd part: the injectable Americans trust is not FDA-approved, and the topical is legal only because cosmetics need no approval.
Buy the salmon one if you like how it feels, and I do, a little. Just keep the two straight: the word on the box has a pedigree the serum only borrows.
